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Sorting nexin 17 prevents lysosomal degradation of 1 integrins by binding to the 1-integrin tail

Atmos Environ 122:382392

Research also points to its potential to regulate the neuroendocrine system, normalise melatonin production, and support immune function

Autoimmunity and Inflammation in SSc Immunological Tolerance Defects in SSc SSc is considered a systemic autoimmune disorder, characterized by the presence of autoantibodies directed against ubiquitous (mostly nuclear auto-antigens) as well as cell-specific autoantigens

It helps regulate inflammatory cytokines, which are the immune signals that go haywire in rheumatoid arthritis and drive joint breakdown